Independent research notes

Understanding research peptides, one plain-language note at a time.

Compound Brief breaks down sourcing, testing, documentation, and storage for people doing their own research — no sales pitch, just what the paperwork actually means and what to check before you trust it.

Independent publication. Not affiliated with any single vendor. See individual articles for sourcing notes and disclosures.

Recent articles

Documentation

How to Read a Certificate of Analysis

What HPLC purity numbers, lot IDs, and identity testing actually tell you — and the fields worth double-checking before you rely on a report.

7 min read
Testing methods

HPLC vs. LC-MS: What's the Difference?

Two testing methods show up on almost every COA. Here's what each one is actually measuring, and why identity and purity aren't the same question.

6 min read
Handling

Storage and Stability Basics for Lyophilized Peptides

Why lyophilized material behaves differently from reconstituted solution, and the temperature mistakes that quietly degrade a sample.

5 min read
Sourcing

What to Actually Check Before Trusting a Vendor's COA

A documentation checklist for telling a genuinely transparent supplier from a site that just put a PDF icon next to the price.

8 min read
Reference

CAS Numbers, Molecular Formulas, and Why They Matter

A quick primer on the identifiers that let you independently verify what compound you're actually looking at.

5 min read

About Compound Brief

Compound Brief is an independent, reader-supported resource for people doing their own research on peptides and research compounds. We write plain-language explainers on documentation, testing methods, and handling — the kind of thing that's usually buried in a PDF or a forum thread. We're not a storefront, and we don't manufacture or sell anything ourselves; some articles reference specific suppliers (including ones the author has direct experience with) when it's relevant to the topic, and any such relationship is noted where it applies.